polypharmacy

A PyTorch and TorchDrug based deep learning library for drug pair scoring. (KDD 2022)

TIP: Tri-graph Interaction Propagation model for Polypharmacy Side Effect Prediction (GRL@NeurIPS, 2019)

Comprehensive bioinformatics platform for precision medicine. Explore drug-gene interactions, pharmacokinetics, clinical trials, and drug repurposing. 20+ research modules. Free & open-source (MIT).

Explainable pharmacovigilance and polypharmacy risk platform for older adults (Python · R).

Detection of Potentially Inappropriate Medications (PIM) and polypharmacy in older adults, based on the 2023 AGS Beers Criteria®. For research and education; synthetic data only.

ᴀ ᴍᴜʟᴛɪ-ᴍᴏᴅᴜʟᴇ ᴄʟɪɴɪᴄᴀʟ ᴅᴇᴄɪꜱɪᴏɴ ꜱᴜᴘᴘᴏʀᴛ ꜱʏꜱᴛᴇᴍ (ᴄᴅꜱꜱ) ʙᴜɪʟᴛ ᴡɪᴛʜ ꜰᴀꜱᴛᴀᴘɪ ᴀɴᴅ ʀᴇᴀᴄᴛ ᴛᴏ ᴍᴀɴᴀɢᴇ ᴘᴏʟʏᴘʜᴀʀᴍᴀᴄʏ. ɪɴᴛᴇɢʀᴀᴛᴇꜱ ᴀ 9-ᴇɴɢɪɴᴇ ᴀɴᴀʟʏꜱɪꜱ ᴄᴏʀᴇ (ʙᴇᴇʀꜱ, ꜱᴛᴏᴘᴘ/ꜱᴛᴀʀᴛ, ᴀᴄʙ), ᴄʜᴇᴄᴋꜱ ʜᴇʀʙ-ᴅʀᴜɢ ɪɴᴛᴇʀᴀᴄᴛɪᴏɴꜱ, ᴀɴᴅ ᴜꜱᴇꜱ ɢᴇᴍɪɴɪ ᴀɪ ᴛᴏ ɢᴇɴᴇʀᴀᴛᴇ ᴇᴠɪᴅᴇɴᴄᴇ-ʙᴀꜱᴇᴅ ᴛᴀᴘᴇʀɪɴɢ ᴘʟᴀɴꜱ.

Explainable polypharmacy ADR prediction using heterogeneous biomedical knowledge graphs (PrimeKG + Decagon) and ClinicalBERT-attributed graph neural networks. MTech thesis, IIT Patna 2026.

Topological Pharmacovigilance & Polypharmacy Phenotyping Platform for GLP-1 Psychiatric Adverse Events (OpenFDA FAERS).

Honest evaluation of emergent 3-drug interaction prediction from FAERS using GNNs

This OpenEnv environment simulates a real clinical safety workflow: triaging drug-drug interactions (DDIs) for older adults with polypharmacy.

Predicting indicated vs. contraindicated drug combinations for polypharmacy and drug repurposing