Geometric deep learning of protein–DNA binding specificity
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Updated
Mar 19, 2025 - Python
Geometric deep learning of protein–DNA binding specificity
DNA analyser IBP - api wrapper for bioinformatics.ibp used for creating R-loop tracker, P53predictor, G4Killer and G4Hunter analysis
Reproducible comparative genomics study investigating human TP53 cancer mutation hotspots across elephant TP53-related sequences, integrating sequence conservation, phylogenetic analysis, computational prioritization, and research software to explore evolutionary conservation of cancer-associated residues.
Comparative evolutionary analysis of recurrent human TP53 cancer mutation hotspots across 56 mammalian species, integrating residue-level conservation, statistical testing, phylogenetic analysis, and cancer-associated mutation data to investigate evolutionary constraints on clinically relevant TP53 residues.
Effect of point mutations on p53 tumor suppressor protein structure : RasMol visualization with RMSD, B-factor & SASA statistical analysis
AlphaFold-powered structural bioinformatics workflow for cancer-associated p53 mutations, including stability, confidence, and hotspot analysis.
Comparative analysis of p53 protein across species
p53/p21 dynamics encode DNA damage and shape proliferation heterogeneity (Comms Biology 2023)
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