Tutorials for the crisprVerse
Computational pipeline for designing multiplexed CRISPR-Cas12a diagnostic panels targeting drug-resistant Mycobacterium tuberculosis
HydraNet is a multi-headed deep learning system for predicting Cas12a guide RNA activity using both gRNA sequence information and pre-computed biophysical features. Models are available trained on 3 Cas12a variants: opCas12a (AsCas12a), D156R LbCas12a, WT LbCas12a.
Annotates CRISPR–Cas repair outcomes from CRISPResso2 allele tables: cut geometry (blunt vs staggered), deletion orientation and size, microhomology context, and which DNA end participates in repair — with publication-ready charts and statistics.
Commensal-sparing CRISPR guide design — target one bacterium, spare the microbiome. Narrow-spectrum, strain-selective, in-browser, free.
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