kircherlab

CADD scripts release for offline scoring. For more information about CADD, please visit our website

With this workflow you can use the output of MPRAsnakeflow (reporter experiment barcode file) together with the MPRA library sequence design file to quantify the MPRA reporter expression. It can quantify variants as well as elements. using BCalm.

Library to analyse, filter and plot MPRA count data.

With this snakemake pipeline you can process your MPRA sequencing data (assignment and count). It is the standard MPRA pipeline of the IGVF consortium and a further development of MPRAflow.

R Shiny website of the Saturation Mutagenesis manuscript

CADD-SV – a framework to score the effect of structural variants

Kircher Lab website