see also http://npppythonscript.sourceforge.net/ (outdated, last update on version 1.0.8, see issue #120)
See https://github.com/bruderstein/PythonScript/blob/master/appveyor.yml to get an rough idea how to build it with VS2022
https://github.com/bitagoras/PyPadPlusPlus